What’s the skinny on the GLP-1 weight loss medications and surgery?

There is growing evidence supporting the recommendation to hold GLP-1 receptor agonists (Ozempic, Wegovy, etc) preoperatively due to concerns over delayed gastric emptying, which can increase the risk of regurgitation and pulmonary aspiration during anesthesia.

Safety is our top priority for all patients. We recommend holding all GLP-1 receptor agonist medications for 6 weeks preoperatively.

This ensures the medication is out of your system and your gut motility is normal on the day of surgery. Postoperatively, you may resume the medication whenever you’d like.

For patients with diabetes who need to hold GLP-1 agonists for an extended period, consulting a with your primary care provider or endocrinologist for alternative antidiabetic therapy is advised to manage blood glucose levels effectively during the perioperative period.